South of the brook it was Ephraim‘s, and north of the brook it was Manasseh’s. And the sea was his border on the west. They reached to Asher on the north and to Issachar on the east.
“They reached to Asher on the north.” “They,” the borders, reached (and touched) the border of the tribe of Asher on the north and the tribe of Issachar on the east.
“east.” Actually, Issachar is northeast of Manasseh, but it is “east” from Asher.